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Sebaceous Cysts in Dogs: Signs, Causes and Treatment

dog breeds that are prone to cysts

Most lumps people call sebaceous cysts in dogs are harmless, and most aren't actually sebaceous. They come from hair follicles, not oil glands, and they fill with a thick, cheesy material. A lump's look and feel can't tell you what it is, though, so I'd have any new one checked with a needle sample.

Key Takeaways

  • The name is a bit off. Most of these are malformed or blocked hair follicles filled with gray, brown or yellowish keratin. They range from 2 mm to more than 5 cm.1
  • A cyst can pass for a more serious lump. Lipomas, abscesses and mast cell tumors can look the same from the outside, and mast cell tumors are the most common malignant skin tumor in dogs.2
  • A needle aspirate sorts most of it out. In a study of dogs and cats with skin lumps, the aspirate result matched the final lab diagnosis 90.9% of the time.5
  • Never squeeze one. Rupture sends keratin into the surrounding tissue and triggers a heavy inflammatory reaction.1,4
  • Removal is the usual treatment. Excision is the treatment of choice,1 but a confirmed cyst that isn't bothering your dog can be watched.

Book a visit soon if a lump is growing quickly, changing color, bleeding or painful, if your dog keeps licking or chewing at it, if one has burst, or if several new lumps appear. Call (519) 896-0532 or book online. Outside our hours, go to the nearest emergency hospital.

What are sebaceous cysts in dogs?

A sebaceous cyst is a closed sac under the skin filled with a thick, cheesy material. The proper name is usually follicular cyst, and you'll also hear infundibular or epidermal cyst. Merck describes most keratinized skin cysts in dogs as malformations of the hair follicle.1

The contents are keratin, the protein that makes up hair and the outer skin. It's gray, brown or yellowish and crumbly, like soft cheese.1 Cysts are usually single, freely movable under the skin and slightly compressible. They run from a couple of millimeters to more than 5 cm.1

True sebaceous gland growths exist too, but they're a separate group of tumors that are common in older dogs and often multiple.2 A needle sample or biopsy is how we tell them apart.

What causes sebaceous cysts in dogs?

The sac forms when a hair follicle develops abnormally or gets plugged, and keratin builds up inside with nowhere to go.1 Several things make that more likely.

  • Genetics. Boxers, Shih Tzus, Miniature Schnauzers, Old English Sheepdogs, Rottweilers, Doberman Pinschers and Bullmastiffs are the breeds reported as predisposed.4
  • Pressure and friction. Skin that's rubbed or pressed on a hard floor can plug follicles, which is why cysts turn up on spots like the elbows. Not every elbow lump is a cyst, though. Calluses are common there too.
  • Injury. Trauma that disrupts the skin can leave a follicle blocked and inflamed.

Where are sebaceous cysts usually located?

Most appear on the head, neck, trunk and upper limbs. They can show up in the ear canal and around the rear end too.

Cysts are usually single, but some dogs grow several. In young dogs, a cluster on top of the head may be congenital. A lump between the toes is a different problem, and we cover those in our post on interdigital cysts.

What do sebaceous cysts in dogs look like?

Round raised lump with a small dark pore at its center and pink skin around it, on the shaved back of a tan dog
A follicular cyst with a visible central pore.

A cyst feels like a well-defined bump, firm to soft, sitting in or just under the skin. Many have a small pore or dark plug at the center. Some look slightly bluish.

A cyst that bursts releases a thick yellow-brown or gray material. Inflamed ones can be sore or itchy, and the skin around them may turn red and swollen. If bacteria get in, you can end up with a secondary skin infection, which we explain in our post on pyoderma.

Ruptured cyst on a white dog's skin, a raw red open lump surrounded by pink inflamed skin, held open between two fingers
A ruptured cyst, red and inflamed.
Three raised cysts, each in its own clipped patch of skin, along the back and hip of a tan dog
Several cysts on one dog.

How can you tell a cyst from other lumps on a dog?

You can't tell by looking or feeling. A lipoma, an abscess and a mast cell tumor can all pass for a cyst, and Merck says identifying skin tumors should be left to a veterinarian.2

LumpHow it often feelsOther cluesWhat I'd do
Follicular ("sebaceous") cystRound, firm to soft, movableMay have a central pore. Releases cheesy material if it bursts.1Aspirate. Then watch it or remove it.
LipomaSoft, movable, often on the trunk or upper legs3Benign fat tumor, most common in older, overweight dogs2Aspirate. Excision is curative if you want it gone.3
AbscessWarm and painfulOften follows a bite or wound. May drain pus.Needs treatment. Book a visit soon.
Mast cell tumorVaries. Can mimic a cyst or a lipoma.The most common malignant skin tumor in dogs2Aspirate before anything else.

How are sebaceous cysts diagnosed in dogs?

Diagnosis starts with an exam and, in most cases, a needle sample. I would suggest the needle sample for any lump we haven't identified before.

  1. Visual inspection. We note the lump's size, location and color, and whether the skin around it looks inflamed or infected.
  2. Palpation. We feel its consistency, how freely it moves and whether it's attached to deeper tissue.
  3. Fine needle aspiration. We draw a few cells or a little material through a thin needle and look at it under a microscope. A cyst shows keratin and keratinized skin cells, and that separates it from a lipoma or a mast cell tumor.2,4

Cytology is reliable but not perfect. In a veterinary pathology study comparing aspirates with final lab results, the aspirate matched the diagnosis in 90.9% of cases. When it called a lump "not a tumor," it was right 68.7% of the time.5 That's why I'd suggest removing any lump that keeps changing or that the aspirate can't explain, and sending it to a lab.

What are the treatment options for sebaceous cysts in dogs?

Once a lump is confirmed as a cyst, you have two reasonable options: remove it or watch it. Excision is the treatment of choice,1 but cysts are benign, so watching is fine for a small one that isn't bothering your dog.

I would recommend removal if a cyst is growing, keeps rupturing, gets infected, sits where it rubs, or if we can't be sure what it is. Removal isn't always practical for a dog with dozens of them. If surgery makes sense, you can read about surgery at Kingsdale.

If you're watching one, measure it and take a photo next to a coin once a month. A change in size, color or feel is a reason to book a recheck.

Don't squeeze it. Squeezing can push keratin into the surrounding tissue, which sets off a heavy foreign body reaction and often turns a quiet lump into a sore one.1,4

  • Do get any new lump aspirated. It's the quickest way to check for a mast cell tumor.2
  • Do measure and photograph a lump you're watching. Monthly is enough.
  • Don't squeeze, pop or poke a cyst. You risk inflammation and infection.1
  • Don't assume a lump is a cyst because it looks like one. Appearance alone isn't enough to tell.2

FAQs

Can sebaceous cysts in dogs become cancerous?

A true cyst is a benign sac and doesn't turn into cancer. The risk is a different lump that looks like a cyst. Lipomas, abscesses and mast cell tumors can all feel similar, and mast cell tumors are the most common malignant skin tumor in dogs. A fine needle aspirate tells them apart, so I would suggest having any new or changing lump checked rather than assuming it's a cyst.

Are certain dog breeds more prone to developing sebaceous cysts?

Yes. Boxers, Shih Tzus, Miniature Schnauzers, Old English Sheepdogs, Rottweilers, Doberman Pinschers and Bullmastiffs are reported as predisposed. Any dog can get one, and some dogs grow several.

Should I squeeze my dog's cyst?

No. Squeezing can push the cyst's keratin into the surrounding tissue, which triggers a heavy inflammatory reaction and often an infection. If a cyst has burst on its own, stop your dog from licking it and call us so we can have a look.

Does every cyst need to be removed?

No. Removal is the treatment of choice, but once a lump is confirmed as a cyst it's reasonable to watch a small one that isn't bothering your dog. I would recommend removal if it's growing, keeps rupturing, gets infected, sits where it rubs, or if we can't be sure what it is.

Sources

  1. Merck Veterinary Manual. "Epidermal and Hair Follicle Tumors in Animals." Integumentary System. merckvetmanual.com.
  2. Merck Veterinary Manual. "Tumors of the Skin in Dogs." Dog Owners. merckvetmanual.com.
  3. Merck Veterinary Manual. "Connective Tissue Tumors in Animals." Integumentary System. merckvetmanual.com.
  4. Cornell University College of Veterinary Medicine, Animal Health Diagnostic Center. "May 2015 Case of the Month." eClinpath. eclinpath.com.
  5. Ghisleni G, Roccabianca P, Ceruti R, Stefanello D, Bertazzolo W, Bonfanti U, Caniatti M. "Correlation between fine-needle aspiration cytology and histopathology in the evaluation of cutaneous and subcutaneous masses from dogs and cats." Veterinary Clinical Pathology. 2006. doi.org.
Dr. Brad Hinsperger

Written by

Dr. Brad Hinsperger, B.Sc., DVM

Dr. Hinsperger is a practicing veterinarian with 20 years of dedicated experience in small animal medicine and surgery at Kingsdale Animal Hospital.

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